个人简介:
陈飞,1990年生,湖北孝感人。副研究员,硕士生导师,湖南省优青。现主持国家自然科学基金青年项目、湖南省自然科学基金优青项目、湖南省教育厅优青项目、湖南省自然科学基金青年项目、中南大学研究生教育教学改革项目。作为核心骨干参与中德合作交流项目、国自然面上项目2项、中南大学前沿交叉项目。本科毕业于华中科技大学同济药学院;硕士毕业于国家纳米科学中心,师从梁兴杰教授;博士毕业于德国马普高分子研究所,师从Kartherina Landfester教授;博士后工作于德国明斯特大学医学院生理病理研究所,合作导师Seraphine Wegner教授。
主要研究方向为:针对环境、生命科学中一系列分析检测及疾病治疗的关键科学问题,开展了以分子探针创新构建用于生物成像、疾病诊断与治疗的研究工作。
近年在以第一/通讯作者在Adv. Funct. Mater.、Acta Pharm. Sin. B.、Chem. Eng. J.、Matter、Biomater. Res.、ACS Sens.、ACS Synth. Biol.、ACS Appl. Mater.、Mol. Pharmaceutics.等国际期刊上发表多篇研究成果,其中NI指数期刊1篇,影响因子>10的文章共6篇,影响因子>15的文章共3篇。
联系方式:
电子邮箱:fechen@csu.edu.cn
代表性研究论文:
1. Liu, X., Ren, Y., Fan, D., Huang, S., Ma, Y., Ding, J., Luo, Z., Chen, F., * Zeng, W. * Shining Light on Multidrug-Resistant Bacterial Infections: Rational Design of Multifunctional Organosilver-Based AIEgen Probes as Light-Activated Theranostics for Combating Biofilms and Liver Abscesses. Adv. Funct. Mater. 2023, 2304974. (IF= 19.0)
2. Fan, D.; Liu, X.; Ren, Y.; Luo, Z.; Li, Y.; Dong, J.; Wegner, S. V.; Chen, F.;* Zeng, W. Harnessing antimicrobial peptide-coupled photosensitizer to combat drug-resistant biofilm infections through enhanced photodynamic therapy. Acta Pharmaceutica Sinica B 2023. DOI: 10.1016/j.apsb.2023.12.016. (IF= 14.5)
3. Zheng, F., Ma, Y., Ding, J., Huang, S., Zhang, S., Huang, X., Feng, B., Zeng, H., Chen, F., * Zeng, W. * Ratiometric and discriminative visualization of autophagic processes with a novel dual-responded lysosome-specific fluorescent probe. Biomaterials Research 2023, 27(1), 66-77.(IF= 11.3)
4. Feng, B.; Ma, Y.; Zheng, F.; Huang, X.; Feng, X.; Zhang, K.; Liu, L.; Chen, F.;* Zeng, W., * Development of near-infrared lysosomal pH-activatable fluorescent probe for real-time visualization of autophagy progression. Chemical Engineering Journal 2023, 464, 142554.(IF= 15.1)
5. Huang, X.;1 Chen, F.;1 Ma, Y.; Zheng, F.; Fang, Y.; Feng, B.; Huang, S.; Zeng, H.; Zeng, W., De novo design of a novel AIE fluorescent probe tailored to autophagy visualization via pH manipulation. Biomaterials Research 2023, 27 (1), 20-37.(IF= 11.3)
6. Liu, X.; Fan, D.; Ren, Y.; Huang, S.; Ding, J.; Liu, M.; Wegner, S. V.; Hou, J.; Rong, P.; Chen, F.;* Zeng, W., * Photo-Activable Organosilver Nanosystem Facilitates Synergistic Cancer Theranostics. ACS Appl. Mater. Interfaces 2023, 15 (1), 711-722.(IF= 9.5)
7. Fan, D.; Liu, X.; Ren, Y.; Bai, S.; Li, Y.; Luo, Z.; Dong, J.; Chen, F.;* Zeng, W., *Functional insights to the development of bioactive material for combating bacterial infections. Front. Bioeng. Biotechnol. 2023, 11, 1186637.(IF= 5.7)
8. Chen, F.; Dong, J.; Sun, W.; Di Iorio, D.; Wegner, S. V.; Zeng, W. Editorial: Construction of smart materials for biomedical application. Frontiers in Bioengineering and Biotechnology 2023, 11, 1278243. doi: 10.3389/fbioe.2023.1278243.(IF= 5.7)
9. Chen, F., Zeng, W., and Wegner, S. V. (2022). Ultrasound-activated bacteria with thermostat controls as living therapeutics. Matter 5, 2416–2419. (IF= 18.9)
10. Liu, X.; Fan, D.; Feng, X.; Zheng, Y.; Wegner, S. V.; Liu, M.; Chen, F.;* Zeng, W. * (2022). Breaching Bacterial Biofilm Barriers: Efficient Combinatorial Theranostics for Multidrug-Resistant Bacterial Biofilms with a Novel Penetration-Enhanced AIEgen Probe. ACS Appl. Mater. Interfaces 14 (37), 41671-41683.(IF= 9.5)
11. Zheng, F.; Huang, X.; Ding, J. P.; Bi, A.; Wang, S.; Chen, F.; * Zeng, W., * NIR-I Dye-Based Probe: A New Window for Bimodal Tumor Theranostics. Frontiers in Chemsitry 2022, 10 (1), 1-23.(IF= 5.5)
12. Song, R.; Ma, Y.; Bi, A.; Feng, B.; Huang, L.; Huang, S.; Huang, X.; Yin, D.; Chen, F.; * Zeng, W., * Highly selective and sensitive detection of arsenite ions(iii) using a novel tetraphenylimidazole-based probe. Analytical Methods 2021, 13 (42), 5011-5016. (IF= 3.1)
13. Chen, F.; Wegner, S. V., Photoswitchable bacteria-bacteria adhesions enable the control of multicellular bacterial communities by using blue light. ACS Synthetic Biology 2020, 9 (5), 1169–1180. (IF= 4.7)
14. Chen, F.; Rachel L. Warnock, Jan Roelof Van der Meer,Wegner, S. V., Bioluminescence-Triggered Photoswitchable Bacterial Adhesions enable Higher Sensitivity and Dual-readout Bacterial Biosensors for Mercury. ACS Sensors 2020, 5 (7), 2205–2210. (IF= 9.618)
15. Chen, F.; Ricken, J.; Xu, D.; Wegner, S. V., Bacterial Photolithography: Patterning Escherichia coli Biofilms with High Spatial Control Using Photocleavable Adhesion Molecules. Advanced Biosystems 2019, 3 (3), 1800269. (IF= 4.053)
16. Chen, F.; Wegner, S. V., Implementation of Blue Light Switchable Bacterial Adhesion for Design of Biofilms. Bio-protocol, 2018, 8 (12), e2893.
17. Chen, F.; Wegner, S. V., Blue Light Switchable Bacterial Adhesion as a Key Step toward the Design of Biofilms. ACS Synthetic Biology 2017, 6 (12), 2170-2174.(IF=4.7)
18. Zhao, Y.;1 Chen, F.;1 Pan, Y.; Li, Z.; Xue, X.; Okeke, C. I.; Wang, Y.; Li, C.; Peng, L.; Wang, P. C.; Ma, X.; Liang, X. J., Nanodrug Formed by Coassembly of Dual Anticancer Drugs to Inhibit Cancer Cell Drug Resistance. ACS applied materials & interfaces 2015, 7 (34), 19295-305.(IF= 9.5)
19. Chen, F.; Zhao, Y.; Pan, Y.; Xue, X.; Zhang, X.; Kumar, A.; Liang, X. J., Synergistically Enhanced Therapeutic Effect of a Carrier-Free HCPT/DOX Nanodrug on Breast Cancer Cells through Improved Cellular Drug Accumulation. Molecular pharmaceutics 2015, 12 (7), 2237-44.(IF= 4.9)
20. Kumar, A.;1 Chen, F.;1 Mozhi, A.; Zhang, X.; Zhao, Y.; Xue, X.; Hao, Y.; Zhang, X.; Wang, P. C.; Liang, X. J., Innovative pharmaceutical development based on unique properties of nanoscale delivery formulation. Nanoscale 2013, 5 (18), 8307-8325.(IF= 6.7)