胡高云,教 授

药物化学系

电话: (731) 82650371

传真: (731) 82650370

电子邮箱:hugaoyun@csu.edu.cn

教育经历

1979-1983北京医学院药学系（现北京大学药学院）药物化学专业毕业，获学士学位

2009-2010 Rutgers, The State University of New Jersey药学院访问学者

课题组介绍

http:/info/1101/2160.htm

研究领域

合成药物化学: 抗纤维化药物和抗糖尿病肾病药物的设计与合成；基于新机制的抗肿瘤药物的设计与合成；基于新靶点的抗炎药物的设计与合成。

1.Ling Wu , Bin Liu , Qianbin Li , Jun Chen , Lijian Tao and Gaoyun Hu* , Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives Molecules 2012, 17, 1373-1387

2.Jun Chen, Miao-Miao Lu, Bin Liu, Zhuo Chen, Qian-Bin Li, Li-Jian Tao, Gao-Yun Hu*, Synthesis and strrelationship of 5-substituent-2(1H)-pyridone derivatives as anti-fibrosis agents Bioorganic & Medicinal Chemistry Letters 2012, 22, 2300–2302

3.Chun Wu, Yanpeng Hu, Qianbin Li, Limei He, Jun Chen, Zeneng Cheng, Yuanjian Li,and Gaoyun Hu*, Synthesis, Pharmacokinetics, and Pharmacodynamics Studies of Valsartan Peptide Derivatives Arch. Pharm. Chem. Life Sci. 2012, 345, 393–400

4.Zhuo Chen , Gaoyun Hu,*, Dai Li , Jun Chen , Yuanjian Li , Huayong Zhou , Ye Xie, Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1) Bioorganic & Medicinal Chemistry 2009, 17 , 2351–2359

5.Hua Yang, Gao-Yun Hu,* Jun Chen, Yi Wang and Zhong-Hua Wang, Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone Bioorganic & Medicinal Chemistry Letters 2007, 17 , 5210–5213